The second-youngest U. S. Vice President ever was Richard Nixon. He was 40 years and eleven days of age when he took office in 1953.
Richard M. Nixon (the second-youngest Vice President in U.S. history)
14th Vice President John C. Breckinridge (36)
John C. Breckinridge, the 14th U. S. Vice President (1857-1861), was 36 when he was sworn in (he was 35 when elected). He was the only U. S. Vice President to date under the age of 40. The second-youngest Vice President, Richard Nixon, was sworn in 11 days after his 40th birthday in January, 1953.
John Adams was the second president and Thomas Jefferson was the second vice president.
John C. Breckinridge
Both the youngest U.S. Vice President, John C. Breckinridge, and the oldest, Alben W. Barkley, were from Kentucky.
Gervais Rufyikiri is the Second Vice President of Burundi.
Theodore Roosevelt still holds the distinction of being the nation's youngest President. He was William McKinley's Vice President, and he was 42 years of age when he was sworn in as President following McKinley's assassination in 1901.
John F. Kennedy was the second youngest president ever at 43. He was the youngest to be elected but the youngest president ever was Theodore Roosevelt who assumed office after the assassination of William McKinley.
Abdul Karim Khalili is the Second Vice President of Afghanistan.
Thomas Jefferson was the second (elected) Vice President of the US