Clash By Night was a 1952 black and white film. It had two leading ladies with equal billing on the promotional material. The actresses were Barbara Stanwyck and Marilyn Monroe.
Ali MacGraw
Kristen Carpenter has: Played Desi in "The Long Road" in 2008. Played Lonna in "Pompe" in 2010. Played Blakes in "The Greatest Script Ever Written" in 2011. Played Jenny in "Wingman" in 2012. Played Leading Lady in "Turn the Night Up" in 2013. Played Audrey Night in "Star Power" in 2014.
Penélope Cruz
Julie Christie played Lara in Dr. Zhivago.
Dana Carvey
Anne Hathaway but the devil is played by Meryl Streep.
The opposite of a Leading Lady is a Leading Man. Another form of Lading Lady is Woman of the Hour and the opposite would be Man of the Hour.
If you'r asking about the movie Phsyco, then the killer (Norman Bates) is played by Anthony Perkins, and the leading lady is played by Janet Leigh.
Shirley Anne Field played the not too bright Doreen, who was the girlfriend, but the married affair that got Arthur beaten up at Goose Fair was with Rachel Roberts (Brenda)
The Leading Lady - 1911 was released on: USA: 18 April 1911
The Leading Lady - 1913 was released on: USA: 24 November 1913
The cast of The Leading Lady - 1913 includes: Ned Finley as Jack Edith Storey as Helen Marsden - the Leading Lady Earle Williams as Marsden