Kevin Spacey plays the killer, John Doe, in Se7en(1995).
The movie Seven, also written Se7en.
Sand
The killer in Scream is known as Ghostface. In the movie he is a serial killer, but he is a fictional character.
The movie "Henry Portrait of a Serial Killer" was released in the year of 1986. The plot of the movie, "Henry Portrait of a Serial Killer" is a scary mystery based on a true story.
Jeff Daniels
fredy vs Jason
chucky
chucky is a serial killer from the movie child's play.
Not that I have ever heard of.
jill
Charleze Theron was riviting as female serial killer Aileen Wuornos, in the Patty Jenkins movie Monster. Wuornos was executed in 2002 after confessing to the murder of 7 men in Florida.
In the movie The Red Dragon, Francis Dolarhyde is a fictional character and the main antagonist. He was called the tooth fairy. He was the serial killer in that movie.