Russell Crowe (known for Gladiator) turned down the role in 1999.
Hugh Jackman is known for his role as wolverine in the x-men film series
There was two, actually. Will Smith and Nicholas Cage both turned it down.
Hugh Jackman played Wolverine in the X-Men movies including X-Men Origins: Wolverine.
Yes, she turned it down due to moral reasons
true
Orlando Bloom
Julia Roberts
Sean Connery was the very first choice for the role of Simon Gruber. He turned down the role, saying that he didn't want to play such a diabolical villain.
Julian Glover
Gene Hackman
Halle Berry
Many actresses turned down the role of Annie Reed in Sleepless in Seattle (1993). They include:Natasha RichardsonNicole KidmanJulia RobertsKim BasingerMichelle Pfeifferjennifer Jason LeighJodie Foster