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It was one of the earliest Spanish missions in California (founded 1772).
It is one of the earliest surviving lists of laws from the early Civilizations.
Jamestown, Plymouth, Massachusetts Bay, Rhode Island
Wilhelm Wundt (1832-1920) was the first person to call himself a psychologist. In 1879, he founded one of the first psychological laboratories in Leipzig, Germany.
Polytheism, the worship of more than one god, is considered the earliest formal religion. Polytheism goes back so far into antiquity, with origins in more than one region of the world, that it is not possible to establish just where and when it was really founded.
The Chester Racecourse is one of the oldest homes to horse racing, being founded all the way back to dates in the earliest years of the sixteenth century.
The GenTeal brand is manufactured by Alcon Laboratories. Founded in 1945, Alcon has grown from a small ophthalmic shop to the second-largest division of Novartis, one of the most successful and respected healthcare companies in the world.
No one knows who orriginally found it. The earliest found use of it was in http://wiki.answers.com/wiki/Çatalhöyük, in modern day turkey. Wikipedia it, stupid.
Underwriters Laboratories and perhaps Consumer's Reports.
ENIAC was one of the nation's earliest computers.
Olmec
Believe it or not, prostitution is actually one of the earliest recorded businesses.