You don't know until after the event.
Sheamus won the wwe championship and Rey Mysterio won the world heavyweight championship
The winner of the fatal four way match will be randy orton
Rey Mysterio
Sheamus
John Cena defeated Edge, Randy Orton and Shawn Michaels in a Fatal Four Way match defended and retained the WWE Championship.
John Cena
Shamus will at fatal 4 way because it is all scripted.
WrestleMania XXVI - Jack Swagger -Cashed it in on SmackDown, then won World Heavyweight Championship from Chris Jericho. (And lost it at:) Fatal-4-Way -to Rey Mysterio in a Fatal-4-Way Match
He was in a Fatal 4-Way match for the World Heavyweight Championship against Undertaker(c), Batista, and CM Punk.
John Cena defeated Kane, Randy Orton, and Roman Reigns to retain his WWE World Heavyweight Championship.
He has been world heavyweight champion two, defeating Kurt Angle and Randy Orton in a triple threat match at WrestleMania 22 and then after winning it in a fatal 4 way match at the PPV fatal four way.
Rey Mysterio Defeated Big Show Jack Swagger and CM Punk - Fatal 4 Way For The World Heavyweight Championship Kofi Kingston Defeated Drew Mcintyre - Intercontinental Championship Evan Bourne Defeated Chris Jericho Alicia Fox Defeated Maryse Eve and Gail Kim - Divas Champion The Hart Dynasty (Tyson Kidd David Hart Smith, Natalya) Defeated The USOS (Jimmy Jey Uso and Tamina) - Six Person Intergender Match The Miz Defeated R Truth - U.S Championship Sheamus Defeated John Cena Edge Randy Orton - Fatal 4 way for the WWE championship