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Brains over brawn, so brainiac.
Wiki User
∙ 13y ago
Brainiac's immense intelligence and advanced technology would likely give him the upper hand over Spider-Man in a direct confrontation, as Brainiac has vast mental abilities and powerful weapons at his disposal. Spider-Man's agility and spider-sense may provide some resistance, but Brainiac's sheer power and intellect would likely prevail in the end.
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