Barehanded, the two guys probably wouldn't even have a chance against a wolf, especially since it is such a fast and effective hunter. Two men with knives or clubs (NOT rifles or swords, as those are hardly effective against a wolf or dog except for use as clubs, especially in a close-quarter-combat situation) might have a chance, but they would have to be good fighters and have the ability to wield such weapons in a manner that is instinctual to them. Otherwise the wolf would win hands (or paws) down.
In a battle between a hyena and a wolf your answer is a wolf
Hmm.. maybe a Mexican wolf
the wolf
if it were a gray wolf then maybe the wolf would win.
Wolf, but if it gets bitten, both will die. Tie.
A horse's strong, muscular hooves can crush the wolf by stomping it and kicking its head.
Possibly the 5 men, but wolf attacks on humans are very rare.
wolf
A wolf.
Wolf.
A wolf would eat it.
Wolf.