recessive
Tay-Sachs disease is a human genetic disorder.
A cultural item which has persisted to this day but no longer really gratifies any human desire is “titles”. Titles conferred a status symbol. The acquisition of such an item must be terribly expensive or very difficult to come by otherwise it holds no meaning.
The disease that affects human sand grazing animals is called the plague.
That will vary from disease to disease and organ to organ.
Something that did not end, such as: "The rain persisted all night long."
No.
"I persisted in my efforts until I achieved my goal.""Our coach persisted in having us practice until we could do a perfect free-throw.""Although the hurricane had passed, windy weather persisted for about a week."
it may have to depend on the type of disease it is....
Creutzfeldt-Jakob disease.
A disease doesn't change the number of bones (some few exceptions exist).
The most widespread human disease caused by flukes would be schistosomiasis.