By only being conducted in one direction, action potentials allow for fast, direct communication between brain and the peripheral tissues. A good analogy for the one-way function of action potentials is the idea of a one way street. When a car drives the wrong way on a one-way street, the normal drivers are confused, and things can go wrong very easily. For a physiological answer to your question, the ion channels in the axon behind an action potential that just passed have become hyperpolarized compared to their resting state. This means they are not as sensitive as normal to any given electrical impulse (ie. action potential). Because of this, the action potential won't go back towards the direction it came from, because the channels that would have to be opened to allow this are very hard (temporarily) to re-open. The electrical energy of the impulse will favor going in the forward direction instead of going back, because going forward it does not have to overcome such hyperpolarized ion channels, and instead can move forward with relatively little resistance.
thick myelinated axons
C. neuromuscular junctions
decreasing amplitude
The most rapid action potentials are conducted on myelinated axons, specifically those with a larger diameter. Myelination and a larger diameter help to increase the speed of conduction by decreasing capacitance and resistance.
Action potentials travel in one direction because of the refractory period, which prevents the neuron from firing again immediately after an action potential has been generated. This ensures that the signal moves in a linear fashion along the neuron.
Action potentials propagate in one direction because of the refractory period, which is a brief period of time after an action potential where the neuron is unable to generate another action potential. This ensures that the signal travels in a linear fashion along the neuron and does not backtrack.
Action potentials are conducted along the cell plasma membrane, triggering the release of calcium ions from the sarcoplasmic reticulum. The calcium ions then bind to troponin, initiating the sliding of actin and myosin filaments, leading to muscle contraction.
Dendrites primarily conduct graded potentials, which are local changes in membrane potential. These graded potentials can accumulate and trigger an action potential in the axon hillock if they reach a certain threshold. Action potentials are then conducted along the axon.
A common feature of action potentials is their all-or-nothing nature, meaning once the threshold is reached, the action potential will always fire at full amplitude. Additionally, action potentials are propagated in one direction, from the cell body down the axon to the axon terminal. They have a consistent shape and duration, regardless of the stimulus strength.
The time between action potentials is known as the refractory period, during which the neuron cannot generate another action potential. This period is essential to ensure that action potentials travel in one direction and allows the neuron to recover before firing again. The refractory period can vary but generally lasts around 1-2 milliseconds.
The FREQUENCY of action potentials that are conducted into the central nervous system serves as the code for the strength of the stimulus. This frequency code is needed because the amplitude of action potentials is constatnt (all or none). Acting through changes in action potential frequency, tonic receptors thus provide information about the relative intensity of a stimulus.
Action potentials typically do not occur in dendrites; instead, they usually originate in the axon hillock of a neuron. Dendrites primarily receive synaptic inputs and generate graded potentials, which can lead to the initiation of an action potential if the membrane potential reaches the threshold at the axon hillock. However, some specialized types of neurons, like certain types of sensory neurons, may exhibit local regenerative potentials in their dendrites. Overall, the main role of dendrites is to integrate incoming signals rather than generate action potentials.