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Marburg and Ebola are extremely infectuous, especially in hospital settings which may lack proper prophylactic protocols, where it's so frequently treated (in at least one breakout, Ebola Zaire was passed by nurses who had run out of hypodermic needles, and were re-using the same needle, thus spreading the disease). The symptoms of filoviruses are very similar to other viral antigens that aren't as lethal, so frequenly Ebola is misdiagnosed. And victims of Ebola generally express no immune reaction, thus the disease has free range.

It should be noted, however, that Ebola is very low on the list of worldwide disease realted mortality, way below Typhus and many others,

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Q: Why aren't all viruses as deadly as Marburg and Ebola?
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