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Low air pressure can't actually cause your blood to boil. Low atmospheric conditions are an environment fairly dangerous to our bodies because there's much less oxygen available than we're used to. Low oxygen levels can especially cause the blood of a person with sickle-cell anemia to lose its oxygen-carrying capabilities. If the person is in a high altitude area for a prolonged period of time, the blood cells (erythrocytes) can lose their nice round little disc shapes and turn into long rods that can clump together and get clogged all over a person's body. If that happens, a person might have damage done to their internal organs, muscle tissue damage (like in the heart), stroke like symptoms, even paralysis. And it definitely doesn't feel very good to have this happen. When your blood cannot carry oxygen, your body tissues will be deprived and cannot carry out cellular respiration to generate ATP which is what your body needs for silly little things like keeping your heart pumping, your brain working, things like that. So even though it can't make your blood "boil" per se, but it can make it change it's shape completely and make you feel like it's boiling.

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Q: Why can low air pressure cause blood to boil?
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