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Beause they have strong intermolecular bonding which decreases their water solubility as water can not get in between the molecules to solvate them. They are also used at a relativley high dose meaning there is a increased chance for these bonds to occur. The bonds cause complexation and precipitation. Sulfonamides can also be precipitated due to the fact that urine is acidic and the pka of some sulfonamides is greater than the pH of urine.
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Crystalluria is the abnormal condition of crystals in the urine.
What kind of drugs commonly has polymorphism?
Polymorphism is common with barbiturates, steroids, and sulphonamides.
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How is a drugs side effect different from the drugs effect?
e.g weed. effect: gets you high side effect: cancer the drugs effect is the intentional effect of the drug. the side-effect is the unintentional effect. eg: pain medication's effect is to ease pain.. it's side-effect is that it often times will make you dizzy. you're not taking it to get dizzy, you're taking it to eliminate pain. therefor the dizziness is the side-effect.
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