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Cells stop growing at a certain size because as they grow larger, they become less efficient because it take longer for the materials that enter the cell to reach the center to be distributed.

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12y ago
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13y ago

There are many reasons why cells do not divide. Here are a few reason (but keep in mind this is not everything)

(1) Cellular program

Many cells are programmed not to divide. They remain in the cell cycle stage known as G0. Although they are metabolically active, they are not dividing or preparing to divide. A good example of this is neurons.

(2) Lack of extracellular signals

Mammalian cells need extracellular signals to tell them to proliferate. Without these signals the cell is not able to progress though the cell cycle and thus not able to divide.

(3) DNA damage

There are "check points" throughout the cell cycle that are designed to check for DNA damage. If damage is detected, the cell is not allowed to proceed though the cell cycle until the DNA is repaired. If the cell is unable to repair the damage it commits "suicide" (apoptosis).

(4) Age

Because of the way in which linear chromosomes are replicated, each round of replication results in the shortening of chromosome. Eventually, the chromosomes are shortened to such an extent that the cell is induced to commit "suicide" (apoptosis).

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14y ago

could be a lot of things but the main problem with growing is deep inside the cell cycle, in G1 phase -could be a problem with de- condensation of chromatin and then the chromosomes can not divide and make another cell
in S phase - the synthesis of histones or duplication of centrioles can be damaged.
in G2 phase- not enought accumulation of factors for cell division.
and pro-phase ,prometaphase, anaphase, telophase and cytokinesis are less problematic stages, most of the problems occur in the interphase( g1 , s &g2).

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9y ago

Cells do not grow. However, they do divide. Cells stop dividing when telomeres at the ends of chromosomes become too short to be replicated.

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8y ago

If you stop eating your body has nothing to make new cells.
contact with other cells

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9y ago

Some factors that can stop normal cells from growing include lack of essential nutrients. It also includes contact inhibition.

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12y ago

Temperature is too cold or too hot. Lack of food. Death of the cells. Presence of poisons. Lack of oxygen if the cells need oxygen.

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13y ago

Death.

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Q: What are some factors that can stop normal cells from growing?
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