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each pathogen has a antigene which the antibodies attach to so each pathogen needs a unique antibodie

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Q: Why do each pathogen need a specific antibody?
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What type of proteins do the white blood cells look for in cell identification?

They look for pathogen specific or pathogen associated proteins presented by MHC molecules. However the also need interactions by co-receptors. These co-receptors are only expressed it the cells are exposed to pathogen associated molecular paterns. Ermm, that might not be the best answer but I hope you get the idea...


Why polyclonal antibody tend to have cross-reaction compare to monoclonal antibody?

Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope, hence monoclonal antibodies are more specific than polyclonal antibodies. However, sometimes MAbs are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since some of the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein this is the reason for the tendency of polyclonal antibodies to have cross-reaction as compared to MAbs. by Victor S Gruezo Jr


Why do you need a different antibody for each type of cell?

Because every cell subject to attack by antibodies has different antigen components on its surface, displaying different " locks " to the antibodies " keys. " This is why a form of selection is used in generating a wide variation in antibody CDR sites.


What does an aerobic pathogen need to survive?

It must have oxygen.


Why polyclonal antibody solution is able to precipitate its antigen protein whereas monlclonal antibody solution has hard time to do so?

Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope. Sometimes, monoclonal antibodies are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein.


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We need vaccines to protect us from infectious diseases and to trigger the immune system to respond with production of antibodies made for that specific pathogen. See the related questions for more details of how this works.


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