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The refractory period is much greater in case of cardiac muscle. It contracts slowly and rhythmically.

but skeletal muscles experience fatigue easily since the expenditure of energy is very high; and as refractory period is very less it does not get time for the removal of the accumulated lactic acid due to anoxygenic respiration.

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14y ago
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10y ago

I would imagine a cardiac muscle has to be more resistant to fatigue as it is in constant use (they move to circulate blood all the time and it is not a conscious function) but a skeletal muscle is moved only when a person intends to do so (or under certain circumstances which don't really effect your question). The heart doesn't get sore from use (mostly) but the legs for example do. This seems like a question of logic, but I am not a medical doctor, so check my facts.

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13y ago

Because they are the muscles that work the most.

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11y ago

because of a chemical substance secreted.

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Q: Why do skeletal muscles fatigue more quickly than smooth muscles?
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