To hold more oxygen.
It will decrease. In a larger cell, you have less surface area per volume.
smaller surface area
The red blood cell's biconcave shape increases its surface area for diffusion. The lack of a nucleus makes this shape possible.
It is because the capillary wall is only one-cell-thick. In addition, they have a large total surface area in contact with body cell and the blood flow is low.
A small cell will have a larger surface-to-volume ratio.
provides a large surface area for transportation
Tissue
The surface area of large cells is very small without an adequate adaptation. Large cells have many cell folds or Crista within their cell membranes and within the cell to maximize cell's surface area which speeds up the process of cellular metabolism.
To increase the surface area so that the blood cell can carry more haemoglobin and, therefore, oxygen.
If the smaller cells' total volume is at least that of the larger cell then the smaller cells have the greater surface area.
A smaller cell has a higher surface area to volume ratio. A reason for this is volume is cubic (3D) and surface area is 2D so when surface area increases a little bit, the volume increases exponentially. And when the surface area shrinks a little bit, the volume decreases exponentially.
because the sickle cell has small surface. and the ESR is proportional to surface area of red blood cell.