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It actually loses very little mass due to the release of beta particles (electrons and positrons) as the element undergoes radioactive decay. But the loss of alpha particles (He nuclei) represents considerable loss of mass. Depending on the element, the time scale for the loss of mass can vary enormously, from fractions of a second to thousands of years.

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Chesley Jaskolski

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Q: Why does a sample of a radioactive element tend to lose mass gradually?
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