She is acting the flower while being the serpent under it; dissembling so as the better to be able to kill him later.
The Prophecy says Macbeth will be king. Duncan is king. Macbeth cannot be king while Duncan is king. Duncan will not be king when he is dead. Therefore, make Duncan dead.
"Wake Duncan with thy knocking! I wish thou couldst!" Yes, Macbeth regrets killing Duncan.
Lady Macbeth gives a signal to Macbeth to come and do the murder by ringing a bell. "The bell invites me", he says.
Macbeth and Lady Macbeth's castle at Inverness. (It's in Scotland on Loch Ness)
Some significant quotes from Macbeth about killing Duncan include: "Is this a dagger which I see before me, the handle toward my hand? Come, let me clutch thee." - Macbeth, Act 2, Scene 1 "I am settled, and bend up each corporal agent to this terrible feat." - Macbeth, Act 1, Scene 7 "Will all great Neptune's ocean wash this blood clean from my hand?" - Macbeth, Act 2, Scene 2 These quotes highlight Macbeth's internal struggle and guilt surrounding the murder of King Duncan.
Lady Macbeth tries to cover for her husband, Macbeth, by helping him come up with a plan to assassinate King Duncan and then framing Duncan's guards for the murder. She also tries to calm Macbeth's guilt and paranoia by assuring him that their actions are necessary for their ambitions.
He kills the chairman, and he admits it saying he did it out of rage, scaring Duncan's sons more.
The voice tells Macbeth that he will never sleep peacefully again because he has committed murder. It also hints that Macbeth's actions will come back to haunt him in the future.
There is no indication of any closeness between them. Macduff is never much interested in socializing with Macbeth. We first see him when he arrives at Macbeth's castle to see Duncan. Note that it is the king he wants to see, not Macbeth. When Macbeth is named king, Macduff refuses to attend the coronation. He also refuses to come to Lady Macbeth's dinner party. It would appear that he never liked Macbeth much.
Lady Macbeth was an accessory and an accomplice to her husband in the murder of King Duncan I [d. August 14, 1040]. It was in fact she who came up with the plan to help Macbeth [d. August 15, 1057] carry out the killing of his sovereign and the two royal guards without any blunders. She planned to get the guards to drink too much of drugged drinks. They then would be incapable of defending their ruler. Neither would they be capable of defending themselves when Macbeth turned the daggers on them as well.
Well first of all, Lady Macbeth didn't murder King Duncan. She was going to, but for some reason Duncan reminded her of her father and she couldn't bring herself to kill him, so Macbeth murdered the King. He murdered the king so the prophecy the three witches told him would come true....that'd he'd become the king.
It's not so much what she tells him, but how she needles him. She knows that he is sensitive to threats to his masculinity, because of the peculiar idea they have that masculine=courageous=good. So all she has to do is to say, "What? Are you not manly enough to kill Duncan?" and he will come around.