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Cis and trans refers to the different faces of a Golgi complex. Vesicles come into the cis face from the ER and leave from the trans face to the plasma membrane or Lysosomes.
Protein SynthesisEndoplasmic Reticulum-->cis Golgi cisternae --> medial Golgi cisternae --> trans Golgi Cisternae --> Plasma membraneExtra Cellular SpaceAs they are being synthesized, secretory proteins enter the lumen of the endoplasmic reticulum. From the ER, vesicles transport these proteins to the Golgi, where they are sequentially modified and concentrated in a cis-to-trans direction. Secretory vesicles bud from the Golgi and move along cytoskeletal filaments to eventually fuse with the plasma membrane, secreting their protein cargo. Each of these transport steps requires specialized proteins to ensure that the cargo is sent to the proper location and is able to fuse with the target membrane.
The "stacks of pancakes" are vesicles with a trans and cis face.
It is responsible for modifying, packaging, and distributing proteins and other macromolecules. Proteins are assembled by the ribosomes of the rough ER, and then packaged into little parts of the ER membrane. These membrane packages pinch off, creating a small spherical pouch called a vesicle. The vesicles then make their way through the cytosol (the fluid inside the cell), to the nearby Golgi apparatus. Proteins enter the Golgi body through the cis face when their vesicle fuses with the Golgi membrane and opens up, emptying its contents into the cisternae. From there, they begin to make their way through each section of the Golgi apparatus until they reach the trans face. Along the way, they are processed based on their ultimate function and destination.
membrane phospolipids
Cis and trans refers to the different faces of a Golgi complex. Vesicles come into the cis face from the ER and leave from the trans face to the plasma membrane or Lysosomes.
Protein SynthesisEndoplasmic Reticulum-->cis Golgi cisternae --> medial Golgi cisternae --> trans Golgi Cisternae --> Plasma membraneExtra Cellular SpaceAs they are being synthesized, secretory proteins enter the lumen of the endoplasmic reticulum. From the ER, vesicles transport these proteins to the Golgi, where they are sequentially modified and concentrated in a cis-to-trans direction. Secretory vesicles bud from the Golgi and move along cytoskeletal filaments to eventually fuse with the plasma membrane, secreting their protein cargo. Each of these transport steps requires specialized proteins to ensure that the cargo is sent to the proper location and is able to fuse with the target membrane.
lysosomal membrane is formed in ER where is later modified and transfered to the cis face of Golgi apparatus where further procesing release lysosome, at least some of them probaly arise from trans face of the Golgi.
The Golgi body
Cisternal maturation occurs in the Golgi apparatus. This is where the cisternae move, beginning at the cis face and progressing via the medial face to the trans face.
The "stacks of pancakes" are vesicles with a trans and cis face.
Golgi apparatus ship or send vacuoles around the cells. The vacuoles are created in the E.R, where they go to the cis face of the apparatus, are processed, and leave on the trans face.
That's because Golgi complex is really spatially orientated (it does not have any random orientation) in the cell - the "cis" part of Golgi is close to endoplasmic reticulum and the "trans" part of Golgi is distant from endoplasmic reticulum. Proteins and lipids coming from endoplasmic reticulum enter Golgi at its "cis" part and across the Golgi network, they are transported towards the "trans" part, from where they are excreted either to other parts of the cell, or more usually, they are transported to plasmatic membrane.
It is responsible for modifying, packaging, and distributing proteins and other macromolecules. Proteins are assembled by the ribosomes of the rough ER, and then packaged into little parts of the ER membrane. These membrane packages pinch off, creating a small spherical pouch called a vesicle. The vesicles then make their way through the cytosol (the fluid inside the cell), to the nearby Golgi apparatus. Proteins enter the Golgi body through the cis face when their vesicle fuses with the Golgi membrane and opens up, emptying its contents into the cisternae. From there, they begin to make their way through each section of the Golgi apparatus until they reach the trans face. Along the way, they are processed based on their ultimate function and destination.
The transport vesicle transports proteins from the smooth endoplasmic reticulum to the cis side of the Golgi aparatus. The vesicles move from the Smooth ER to the receiving (cis) side of the Golgi aparatus, and then leave though the trans (shipping) face of the Golgi aparatus .
hahaha....
The Golgi apparatus has a structure that is made up of cisternae, which are flattened stacks of membrane usually found in a series of five to eight, or until they fill up the cytoplasm. These cisternae help proteins and cytoplasmic components biochemically react and travel between different parts of the Cell.How the proteins and vesicles pass through the Golgi apparatus structure is clearly represented and understood.According to the vesicular transport model, there are a variety of compartments located between the cis, essentially the beginning of the Golgi apparatus, and the trans, the end. These compartments shuttle along the macromolecules from section to section using membrane-bound carriers. The cisternal maturation model states that the vesicles fuse to each other at the cis face of the Golgi apparatus and are essentially pushed along as new vesicles fuse together behind them.