Unless it is caused by pavement or road conditions, the likely causes are:
Worn U-joints in the drive shaft become more noticeable the faster the vehicle is traveling, and the vibration will still be present if the transmission is shifted into neutral or the clutch is disengaged, allowing the truck to coast.
NO
Yes, either can cause a shake while driving.
A universal joint on the driveshaft going bad.
A car's steering wheel will vibrate when driving if the car's alignment needs to be adjusted.
Bad tires or out of balance tires or driveshafts. Have it checked out.
Loose motor mounts.
Truck driving simulators can be found on various websites specializing in driver training or driving games. Alternatively, truck driving simulators can also be found at driving schools specializing in truck driving training.
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Wheel bearings and allignment. Can be tires as well and sometimes even a bad motor mount.
You might need an alignment.