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In the first stage of glycolysis, there is an initial investment of ATP energy in breaking down a molecule of glucose. The phosphate from this ATP molecule (which later catabolizes to ADP) is transferred to the 6th carbon atom in the glucose molecule. Therefore, the initial investment of energy in glucose creates glucose-6-phosphate.

What is so significant about glucose-6-phosphate? The phosphorylation of glucose makes it more reactive.

Or you could think of it like this: What is the whole point of cellular respiration? It's to break down complex organic material to create energy, right? So a complex molecule, glucose for example, is difficult to break down in the first step. By energizing this glucose molecule, you are breaking the bonds. This breaking of bonds ultimately spurts the whole catabolysis reaction.

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13y ago
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13y ago

Two ATP is needed as an initial investment in order to start glycolysis. The first five steps of glycolysis is energy-harvesting, and thus, the 2 ATP are needed to raise glucose to a higher, more unstable, energy state.

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12y ago

ATP makes it easier to break apart glucose into two three-carbon molecules

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12y ago

Cells need glycolysis because glycolysis does not require oxygen to produce ATP.

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12y ago

Because it takes only two ATP to make about TEN! There's a huge profit for the cell.

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9y ago

Not only in first step, it used in many other steps in the metabolism. The purpose of ATP usage is to provide the chemical energy for the conversion of reaction components.

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13y ago

There will be 2 ATP investment

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Q: Explain why an initial investment of ATP is required for the prepatory steps of glycolysis?
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