Homer Simpson's most popular quote, which he uses the most is, "D'oh!" . He says then when he is frustrated, mad, or feels like a dimwit. He is also known for saying, "Why you little..." at Bart when he is mad.
He probably hates him because he's annoying and weird and he's kind of nerd like and talks very weird. Homer Simpson hates Ned Flanders because he is perfect and loves Jesus. Homer doesn't like going to church because he thinks it is a waste of time.