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Why is it better to take a drug as the active enatiomer instead of the racemic mixture?
Wiki User
∙ 14y ago
Enantiomers can have very different effects on the body, which contains many chiral compounds. While one enantiomer may have a healing medicinal effect, the other can be harmful, or at best, ineffective. While it is much more complicated to make a single enantiomer or separate a racemic mixture, taking a single-enantiomer drug often has a much greater effect.
Wiki User
∙ 14y ago
Taking a drug as the active enantiomer instead of the racemic mixture can be advantageous because the active enantiomer is usually responsible for the desired therapeutic effects, while the inactive enantiomer can contribute to unwanted side effects or have no therapeutic value. By using the active enantiomer, the drug's efficacy can be maximized, potentially reducing side effects and improving patient outcomes. Additionally, testing and developing a single enantiomer may be more cost-effective and efficient compared to handling and studying a racemic mixture.
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What is benzoyl DL-arginine p-nitroaniline hydrochloride?
It is substrate used to measure proteas activity. Trypsin is one of the enzymes it is used for. The compound you mentioned is a racemic mixture and I believe it is only the L form that is an active substrate. Thomas Henriksson, Ph.D.
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