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Enantiomers can have very different effects on the body, which contains many chiral compounds. While one enantiomer may have a healing medicinal effect, the other can be harmful, or at best, ineffective. While it is much more complicated to make a single enantiomer or separate a racemic mixture, taking a single-enantiomer drug often has a much greater effect.

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What is difference between a racemic mixture and a meso compound?

Both are optically inactive, but for different reasons. A racemic mixture contains chiral molecules that, individually, are optically active. But the mixture contains optically active enantiomers, which essentially cancel out each other's optical activity (one enantiomer rotates light one way, the other rotates it back). A meso compound, however, is optically inactive on its own. It can have chiral centers within its structure, but due to symmetry it will still be optically inactive.


How is chiral resolution process?

The separation of a racemic mixture into two optically active forms (+ or −) is known as chiral resolution. Since diastereomers have different chemical and physical properties, they can be separated into corresponding enantiomers by chiral resolution. This method is called enantiomeric enrichment, and it is a process of continuously increasing the percentage of enantiomers until the enantiomeric excess finally approaches 100%./BOC Sciences


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How do you identify isomers?

plane polarised light is being used. A solution of one enantiomer rotates the plane of polarisation in a clockwise direction. This enantiomer is known as the (+) form. A solution of the other enantiomer rotates the plane of polarisation in an anti-clockwise direction. This enantiomer is known as the (-) form. If the solutions are equally concentrated the amount of rotation caused by the two isomers is exactly the same - but in opposite directions. When optically active substances are made in the lab, they often occur as a 50/50 mixture of the two enantiomers. This is known as a racemic mixture or racemate. It has no effect on plane polarised light.


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