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Omeprazole must be taken at least 30 minutes prior to a meal for the medication to be properly absorbed. Omeprazole absorption is significantly impaired when in the presence of food. Omeprazole OTC (over-the-counter) does not work instantly and may take up to 4 days (4 doses) for the medication to reach adequate levels in the blood and be fully effective at significantly reducing stomach acid.

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Q: Why omeprazole is taken 30 minutes before food?
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