Edward was dieing of Spanish Influenza and Esme jumped off a cliff and tried to commit suicide because her son died a few days after his birth.
Esme and Edward were turned into vampires before the start of the Twilight series.
At the beginning of the series, there are 7 Cullens: Dr. Carlisle Esme Emmett Jasper Rosalie Alice and Edward
No. If someone read twilight, Esme is carisles wife, or Edward Cullen's mommy. yea.. good lucky.. bye!
Edward
Edward Sr, and Elizabeth Masen were his biological parents. Carlisle and Esme Cullen are, what he considers, to be his mom and dad.
Charles Evenson :)
Edward (he was dying in a hospital) Esme (she 'fell' off a cliff) Rosalie , and Emmet ( bear attack
probably
Edward Cullen
Carlisle, Esme, Rosalie, Emmett, Alice, Jasper, Edward
rosalie Emmett Alice jasper and edward; then carlisle then Esme
Rosalie, Esme, Carslisle, Jasper, Emmet, Alice, and Edward. So, 7.