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The Europeans had been exposed to many diseases and bacteria prior to coming to America. Their immune systems had adapted to those threats to their personal health, but they still carried the differing ailments with them in one form or another.

When the American people (who had been exposed to fewer diseases - largely due to geographic isolation) encountered the many potent diseases of the Europeans, their immune systems had not yet built up antibodies or resistance to them, so the diseases spread quickly and took many lives during the first few decades of European contact.

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Yazmin Sawayn

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