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In the event that you have accidentally placed a hot sample inside a typical desicator (without stopcock), and partial vacuum build up. Plus heating don't help.

One way to open the desicator is:

PARTY RIBBONS or any thread like material that is fine enough and tough. Place the ribbon to the circumference of the desiccator and pull on both end so the string moves inward towards the center and break d partial vacuum.

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Q: Why would it be difficult to open the desiccator after its contents have cooled?
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