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Absolutely not; they are the exact same thing; one is just designed to last longer than the other before your body breaks it down. Morphine IR and Morphine ER are both morphine; one is instant-release (IR) and the other is extended release (ER). So a UA will definitely detect both, no matter whether it is a slow-release (ER) or a fast-release (IR). Depending on the type of test it will come up positive for 'opiates', or 'morphine' if it is a test that names the actual base substance.

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Q: Will UA distinquish between morphine ir and morphine er?
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