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Excessive (above prescribed dose) use of any product contain Dextromethorphan (DXM, DM) can result in an opiate false positive reading. If you take a dose as prescribed there should not be an issue tho.

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Q: Will a daytime sinus soft gel make you test positive for opiates?
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Opiates - Substances or Conditions which can cause false positivesPoppy SeedsTylenol with codeineMost prescription pain medicationsCough suppressants with Dextromethorphan (DXM)NyquilKidney infection, Kidney DiseaseDiabetes, Liver Diseasewww.passdrugtest.com