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Probably not, Kishimoto hasn't given off any clues that they would be friends, and plus, they're rivals in love. They both have had a crush for Sasuke in the past, and even after Sasuke tried to kill Karin, she stuck with him. Sasuke also tried to kill Sakura, yet Sakura still cares for him and wants him to go back to Konohagakure.
Some other reasons:
They both have headstrong, frank personalities, so I don't think they would be able to become friends.
Karin is a missing-nin, therefore has a bounty over her head, Sakura is a 'good' girl, and she wouldn't associate herself with Karin, atleast I don't think.
Both have light hair colors that would clash together, if they became friends. While Sakura might not care about this, but surely Karin would.
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Does sakura hates karin?
Does karin ever meet sakura? yes. and they hate each other at the moment they do.
Who is stronger sakura or karin?
karin doesn't have very good tai-jutsu. and sakura defeated sasori, karin couldn't do that. karin doesnt have perfect chakra control sakura does, in a battle karin could only locate sakura, not fight her.
Does Sasuke prefer Sakura or Karin?
Most likely, Sasuke is more familiar with Sakura than Karin. The reason as to why this question would be not answered completely would be due to the fact that this question is incomplete. What does he prefer them for? Friends? Maybe even lovers? But most would say Sakura. Sasuke would most likely prefer Sakura over Karin. But they're are no bold hints he cares for either one because Sasuke is seemingly heartless. Sakura was there for sasuke so yeah he might pick sakura over karin.
Does karin kill sakura?
no karin is too weak.
Is sakura prettier than karin?
Obviously SAKURA!! Sakura inherited her super strength from Tsunade!! All Karin can do is just sense chakara! With one punch Karin will probably be injured...but I agree on the first answer... Um actaully karin would own sakura
Karin kills sakura?
no way do you know how strong sakura is one punch from her and karin will be a pile of broken bones and karin is not a good fighter. that is very true...sakura fought many shinobi but karin hasn't fought any one....
Does Sasuke prefer Sakura or Karin better?
of course, sakura will win and of course she is better than karin because karin only knows how to pose when she is taking a pictorial
Will sakura kill karin?
I doubt it.
Is saskue into sakura or karin?
Neither.
Does karin knows about Sasuke and sakura's past?
No she dosen't.In one of the episodes Karin and Sakura cross paths.Both of them don't know eachother.
Does Sasuke ever love sakura?
well He does have little feelings cause there's a huge change in attitude and he hates Karin
How does karin dies?
Sasuke is battling Danzou and Danzou is close to death and is running out of options, so he grabs Karin off guard and and holds her in front of him. He basically took her hostage right in front of Sasuke. Sasuke being the way he is with revenge uses his Chidori/Lightning Blade and stabs the both of them. Karin does not die, but Danzou does. Karin is mortally wounded. Sakura tracks down Sasuke and finds him with Karin lying on the ground next to him. Sasuke says that if Sakura can kill Karin, she can go with him. Sakura is seen thinking, "She has nothing to do with this." Then, Sasuke tries to hit Sakura with Chidori/ Lightning Blade while her back is turned. Karin notices that he will kill Sakura, and she says, "Sasuke... stop." Sakura turns around, and Kakashi appears and stops Sasuke. He tells Sakura to take Karin and heal her until she can talk. So, that is what happens. Karin does not die.
