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yes she probably will because she attacked him once for the sake of her promise with naruto who is one of her best friends (or in shippuden maybe JUST MAYBE SOMETHING even more..) so if she can attack sasuke for naruto she can do it for tsunade there's no way I can imagine sakura watching sasuke kill her beloved teacher in front of her eyes sakura is different in shippuden I love her super human strength,brains,excellent tai-jutsu,healing jutsu & her bravery! sakura rocks!

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