Of course he'll escape, there wouldn't be a show if he was stuck in there forever.
If you mean things that are likely to have recurring themes within the series then: 1. Cracks 2. Myth 3. Pandorica
In "The Pandorica Opens" episode of Doctor Who, a future version of the Doctor gave the sonic screwdriver to Rory by tossing it to him before being sealed inside the Pandorica. This action laid the groundwork for Rory to use the device to release the Doctor from the Pandorica in the subsequent episode, "The Big Bang."
Originally, nothing was. The Pandorica was empty, because it was built to hold the Doctor, after he'd been lured there. He was not in it long though, he'd engineered his own escape, getting Rory to open it from the outside. A mortally wounded Amy was then placed inside, since death is a form of escape, the Pandorica could even prevent that. She then spent the next 2000 years in stasis, until her young future self touched it, giving the Pandorica the DNA information it needed to heal the adult Amy inside.
No it's not real.
The Pandorica was built by an alliance of the Doctor's greatest foes who were under the mistaken belief that the Doctor was responsible for the cracks in the universe. It was built to imprision the Doctor, presumably indefinately.
The Pandorica Opens/The Big Bang
River song left it.
I think he's supposed to have stolen his TARDIS to escape, but theres a bit of a plot hole in that the eleventh doctor somehow got a new TARDIS when he wasn't allowed to return to galifrey
Eleventh Doctor was created in 2010.
A Christmas Special.
Not who, but what. The Pandorica was an elaborate prison created by the Alliance (a coalition of The Doctor's greatest enemies) to hold The Doctor for all eternity. Their reasoning for this was not to be rid of The Doctor for their own gain, but to stop the cracking of the universe, which they believed was The Doctor's doing. In fact it was caused by the TARDIS exploding mysteriously on the 26th of June 2010 (the date of the finale's broadcast).
The Doctor in the future, went back to the Roman time using the transporter that River left behind to give Rory his Sonic Screwdriver. By giving him the sonic screwdriver, he told Rory to go and open the Pandorica with it. He did, and the Doctor found out that he had indeed come from the future, exclaiming "Oh good, I have a future." Rory then, told by the future doctor who wears a Fez and holds a Mop from some musuem, puts the screwdriver into Amy's coat pocket. The Future doctor then finds it in Future amy's pocket.