Yes they can. And have beaten them throughout history!
90% Tosa Inu
Tosa is a large Japanese dog.
Tosa Mitsunobu died in 1525.
Tosa Mitsunobu was born in 1434.
Tosa Mitsuoki was born in 1617.
Endoclita tosa was created in 1958.
Reiko Tosa was born in 1976.
Tanaka Tosa was born in 1820.
Tanaka Tosa died in 1868.
Tosa Inu would probably win, as this ranking system: Tosa Inu -More heaver (77-130 lb.) -Taller (2-2.7 Ft) -Bred to be a dog-fighter (Bonus-Tosa inu is a rare speises!) Dogo Argentino -Big, but not as big (77-88 lb F) (88-99 lb M) -Not as tall (2.1-2.5 Ft) -Bred to be loyal, but not to fight but to hunt deer. But I could see this going 2 ways: 1- The tosa would get tired out because Dogo is more of a swift dog. 2- The tosa would put up too much of a fight for Dogo because dogo is more built for scrawny deer.
Marco Tosa has written: 'Vestiti da sera'
First attack from any of the sides will have an edge. a akita will probably beat a bull mastiff since it has a stronger bite force