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Keep taking the Zoloft as prescribed. Stop the non-prescription pot. Drink plenty of water, eat a balanced diet and do moderate exercise. The effects of the pot will eventually be gone and you should feel yourself in several days. If you tend to have problems with depression, pot and alcohol are not your friends. Leave them alone!

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Q: You've been taking 50mg of zoloft for about a year and you smoked pot twice for the first time yesterday and now you feel depressed is this normal what can you do?
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