it could be your fuel filter or fuel pump, on most f150's there are 2 fuel pumps...1 in the tank, 1 on the fuel rail.
If it's not getting enough fuel it could be the fuel pump or the fuel filter.
check that the fuel filter is not clogged
the fuel pump is getting weak or the motor timing or/ spark advance is off
wont, start,change punp,not getting gas
sounds to me like it has a bad vacuum leak, check around the intake for hissing sounds
check your fuel pump it may not be pumping gas
My 1990 honda accord take off fine but act like its not getting gss after a mile or so. It stalls down. When I mash the gas it want go and cuts off
Mass Air Sensor (MAP) is defective.
sounds like the cat is blocked in the exaust
too many possibilitys.it needs to be scaned to find out why
faulty fuel pump at the gas tank or dirty fuel filter in gas line most likely
I'm not sure what you mean by acts like it is running out of gas....a car runs fine until it runs out of gas...at which point it stops and won't start again until you put gas in. There is no difference in the way it acts on the first or last drop.