Yes it will, because I have guitar hero 3 and 5, and the guitar hero 3 guitar, works with both (as long as the guitar hero guitar is second player on 5).
Guitar Hero controllers work with all Guitar Hero games, which is great! WOO!
The Guitar Hero guitar will work with Rock Band but the Rock Band guitar won't work with Guitar Hero. -Nate
No but in Guitar Hero 5 it will work
Yes they will work
Guitar Hero 2 guitars are the same as the Guitar Hero 1 guitars, so they work with guitar hero 1 and 2. If they are for the same system as Guitar Hero 3, then they will work. But that would only be with the PS2 and Xbox.
Yes, all Guitar Hero guitars are compatible with every guitar hero.
yes
yes it does
Yes
yes
indeed it does.