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It could be the brand. Just like in generic anything, meds are no different. If you filled the brand name the first time, and filled generic the second, this could explain the difference in taste. Also (more of a longshot here) when your sinuses are congested things will taste differently. Are you less congested now that you were when you first had the syrup?

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Q: Your Phenergan w Codeine cough syrup tastes very bitter and not sweet like it usually is Did they give you the wrong medicine?
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