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Maybe zoloft was not doing the expected effect; or their side effects are too strong. Also he could take this decision because effexor XR acts over serotonine AND norepinephrine; is more activating and "energyzing" than zoloft. Zoloft is the gold standard antiperessant in axious-depressive patients, OCD, social phobia...anxious disorders in general

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Q: Your doctor took you off of Zoloft and put you on Effexor you wonder why?
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