Autosomal recessive is one of several ways that a trait, disorder, or disease can be passed down through families.
An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop.
Alternative NamesGenetics - autosomal recessive; Inheritance - autosomal recessive
InformationInheriting a specific disease, condition, or trait depends on the type of chromosome affected (autosomal or sex chromosome). It also depends on whether the trait is dominant or recessive.
A mutation in a gene on one of the first 22 nonsex chromosomes can lead to an autosomal disorder.
Genes come in pairs. Recessive inheritance means both genes in a pair must be defective to cause disease. People with only one defective gene in the pair are considered carriers. However, they can pass the abnormal gene to their children.
CHANCES OF INHERITING A TRAIT
If you are born to parents who both carry an autosomal recessive change (mutation), you have a 1 in 4 chance of getting the malfunctioning genes from both parents and developing the disease. You have a 50% (1 in 2) chance of inheriting one abnormal gene. This would make you a carrier.
In other words, if four children are born to a couple who both carry the gene (but do not have signs of disease), the statistical expectation is as follows:
Note: This does not mean that children will necessarily be affected.
See also:
Autosomal recessive is one of several ways that a trait, disorder, or disease can be passed down through families.
An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop.
Alternative NamesGenetics - autosomal recessive; Inheritance - autosomal recessive
InformationInheriting a specific disease, condition, or trait depends on the type of chromosome affected (autosomal or sex chromosome). It also depends on whether the trait is dominant or recessive.
A mutation in a gene on one of the first 22 nonsex chromosomes can lead to an autosomal disorder.
Genes come in pairs. Recessive inheritance means both genes in a pair must be defective to cause disease. People with only one defective gene in the pair are considered carriers. However, they can pass the abnormal gene to their children.
CHANCES OF INHERITING A TRAIT
If you are born to parents who both carry an autosomal recessive change (mutation), you have a 1 in 4 chance of getting the malfunctioning genes from both parents and developing the disease. You have a 50% (1 in 2) chance of inheriting one abnormal gene. This would make you a carrier.
In other words, if four children are born to a couple who both carry the gene (but do not have signs of disease), the statistical expectation is as follows:
Note: This does not mean that children will necessarily be affected.
See also:
Review Date: 04/26/2010
Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Autosomal dominant, Autosomal recessive, X-linked recessive and X-linked dominant
Autosomal recessive
FAP follows both an autosomal recessive and autosomal dominant pattern depending on which gene you inherit the disease from. If inherited through the APC gene, which is most common, it is autosomal gdthe disease. If inherited through the MUTYH gene it is autosomal recessive, meaning that both parents were carriers of the disease or they both were living with the disease.
heterozygous
No. It is an autosomal recessive disease.
Yes, cystic fibrosis is an autosomal recessive disease.
Recessive Autosomal
Autosomal dominant Autosomal recessive X linked recessive.
Autosomal dominant Autosomal recessive X linked recessive.
About 40% of SCID cases are inherited from the parents in an autosomal recessive pattern.
It is an autosomal recessive trait.
Autosomal dominant, Autosomal recessive, X-linked recessive and X-linked dominant
gene that is not strong
Autosomal recessive
Zellweger syndrome is autosomal recessive.
Alzaymrs is ottosomal dominent
Sex-linked and Recessive