Cushing's disease is a condition in which the pituitary gland releases too much adrenocorticotropic hormone (ATCH). The pituitary gland is an organ of the endocrine system.
Cushing's disease is a form of Cushing syndrome.
Alternative NamesPituitary Cushing's disease
Causes, incidence, and risk factorsCushing's disease is caused by a tumor or excess growth (hyperplasia) of the pituitary gland. This gland is located at the base of the brain.
People with Cushing's disease have too much ACTH. ACTH stimulates the production and release of cortisol, a stress hormone. Too much ACTH means too much cortisol.
Cortisol is normally released during stressful situations. It controls the body's use of carbohydrates, fats, and proteins and also helps reduce the immune system's response to swelling (inflammation).
SymptomsSymptoms usually include:
Skin changes that are often seen:
Muscle and bone changes include:
Women often have:
Men may have:
Other symptoms that may occur include:
Tests are done to confirm there is too much cortisol in the body, then to determine the cause.
These tests confirm too much cortisol:
These tests determine cause:
Treatment involves surgery to remove the pituitary tumor, if possible. After surgery, the pituitary may slowly start to work again and return to normal.
During the recovery process, you may need cortisol replacement treatments. Radiation treatment of the pituitary gland may also be used.
If the tumor does not respond to surgery or radiation, you may get medications to stop your body from making cortisol.
If these treatments are not successful, the adrenal glands may need to be removed to stop the high levels of cortisol from being produced.
Expectations (prognosis)Untreated, Cushing's disease can cause severe illness, even death. Removal of the tumor may lead to full recovery, but the tumor can grow back.
ComplicationsCall your health care provider if you develop symptoms of Cushing's disease.
If you have had a pituitary tumor removed, call if you have signs of complications, including signs that the tumor has returned.
ReferencesStewart PM. The adrenal cortex. In: Kronenberg H, Melmed S, Polonsky K, Larsen PR, eds. Williams Textbook of Endocrinology. Philadelphia, Pa: Saunders Elsevier; 2008:chap 14.
Cushing's disease is a condition in which the pituitary gland releases too much adrenocorticotropic hormone (ACTH). The pituitary gland is an organ of the endocrine system.
Cushing's disease is a form of Cushing syndrome.
Alternative NamesPituitary Cushing's disease
Causes, incidence, and risk factorsCushing's disease is caused by a tumor or excess growth (hyperplasia) of the pituitary gland. This gland is located at the base of the brain.
People with Cushing's disease have too much ACTH. ACTH stimulates the production and release of cortisol, a stress hormone. Too much ACTH means too much cortisol.
Cortisol is normally released during stressful situations. It controls the body's use of carbohydrates, fats, and proteins and also helps reduce the immune system's response to swelling (inflammation).
SymptomsSymptoms usually include:
Skin changes that are often seen:
Muscle and bone changes include:
Women often have:
Men may have:
Other symptoms that may occur include:
Tests are done to confirm there is too much cortisol in the body, then to determine the cause.
These tests confirm too much cortisol:
These tests determine cause:
Treatment involves surgery to remove the pituitary tumor, if possible. After surgery, the pituitary may slowly start to work again and return to normal.
During the recovery process, you may need cortisol replacement treatments. Radiation treatment of the pituitary gland may also be used.
If the tumor does not respond to surgery or radiation, you may get medications to stop your body from making cortisol.
If these treatments are not successful, the adrenal glands may need to be removed to stop the high levels of cortisol from being produced.
Expectations (prognosis)Untreated, Cushing's disease can cause severe illness, even death. Removal of the tumor may lead to full recovery, but the tumor can grow back.
ComplicationsCall your health care provider if you develop symptoms of Cushing's disease.
If you have had a pituitary tumor removed, call if you have signs of complications, including signs that the tumor has returned.
ReferencesStewart PM, Krone NP. The adrenal cortex. In: Kronenberg H, Melmed S, Polonsky K, Larsen PR, eds. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 15.
Reviewed ByReview Date: 12/11/2011
Nancy J. Rennert, MD, Chief of Endocrinology & Diabetes, Norwalk Hospital, Associate Clinical Professor of Medicine, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A pituitary tumor can cause Cushings, however a swelling that compresses the pituitary most usually will cause decreased function, not increased function as seen in Cushings. If the pituitary hormones that direct the adrenals fail, it is called Addisons' Disease.
Huntington's Disease
The disease is called cultimanureity disease
No, this disease is an autoimmune disease.
That will vary from disease to disease and organ to organ.
no, because Cushings disease is when your adrenal glands secrete to much cortosol. Addison's disease is when your adrenal glands sucrete to little cortisol.
hypersecretion of thyroxine leads to grave disease, thyrotoxicoises
It happens, and can be the result of cushings disease which is the opposite of addisons, but this type is caused by the drugs treating the cushings. this link will help you http://www.caninecushings.net/forums
Cushings Disease
Information on Cushings disease can be found online from many different web resources. Some examples of these resources include Mayoclinic and About Cushings.
Could be canine cushings disease
The symptoms of Cushings Disease are a result of an abnormally high amount of Cortisol.
Cushings syndrome or Cushings disease is generally caused by a tumor on the pituitary gland and results metabolic disorders such as insulin resistance, obesity, diabetes, long hair coat, laminitis etc depending on the animal.
laminius colic cushings disease kissing spine etc....
Cushings can be deadly if not treated. GO GET TREATED!
A pituitary tumor can cause Cushings, however a swelling that compresses the pituitary most usually will cause decreased function, not increased function as seen in Cushings. If the pituitary hormones that direct the adrenals fail, it is called Addisons' Disease.
Cushing's Disease is a tumour which is non-cancerous and can be treated either by surgery or medication. http://en.wikipedia.org/wiki/Cushings_disease