Can swelling around pituitary gland lead to cushings?

Answer 1

A pituitary tumor can cause Cushings, however a swelling that compresses the pituitary most usually will cause decreased function, not increased function as seen in Cushings. If the pituitary hormones that direct the adrenals fail, it is called Addisons' Disease.

Answer 2

Yes, swelling around the pituitary gland can lead to Cushing's syndrome if it affects the production of adrenocorticotropic hormone (ACTH). This can in turn stimulate the adrenal glands to produce excess cortisol, causing symptoms characteristic of Cushing's syndrome such as weight gain, high blood pressure, and muscle weakness.