When a person has cancer, sometimes the cancer will metastize to other areas of the body. When cancer has metastizes, the lymph nodes can become involved due to the cancer spreading through the lymphatic fluid.
A sentinel lymph node is the first lymph node that drains a cancer. If a cancer has not spread to the first draining lymph node near a cancer, there is a high likelihood it has not spread elsewhere.
A sentinel lymph node is the first lymph node that drains a cancer. If a cancer has not spread to the first draining lymph node near a cancer, there is a high likelihood it has not spread elsewhere.
A lymph node dissection
A lymph node dissection
A positive sentinel node suggests that cancer cells have spread from the primary tumor to nearby lymph nodes. Further evaluation and treatment, such as lymph node dissection and adjuvant therapy, may be needed to determine the extent of spread and reduce the risk of recurrence.
The only method to identify whether or not a lymph node has cancer cells, is to surgically remove the node and perform examination with a microscope to detect abnormal cancer cells.
Diaphragm cancer, or any cancer that is classified as stage 3 means it has spread to the lymph nodes. The lymph nodes accelerate the spread of the disease.
The American Joint Committee on Cancer (AJCC) TNM system is a staging system that classifies cancers based on their T, N, and M stages, which is to say their Tumor, Node and metastasis. The nodal status refers to the "N" portion of this classification system. The N indicates the presence, if any, of cancer spread to other lymph nodes. The system is: NX: Regional lymph nodes cannot be assessed. N0: Cancer has not spread to regional lymph nodes. N1: Cancer has spread to 1 to 3 lymph node(s) under the arm N2: Cancer has spread to 4 to 9 lymph nodes under the arm N3: Cancer has spread to 10 or more lymph nodes under the arm or also involves lymph nodes in other areas around the breast. The TNM, taken together, yield the stage of breast cancer a patient is in.
The cancer started in the lymph node, but quickly began to spread, since lymph nodes are located throughout the human bodies. Cancerous cells spread throughout a patient's body, destroying the function of healthy cells. If too many cells die like this, organ failure and death result.
Breast cancer most commonly metastasises first to lymph nodes in the axilla of the same side as the affected breast. In more advanced disease, the cancer commonly metastasises to lymph nodes in other regions, to bone, to the liver, and/or to the lungs, and later possibly also to the contralateral breast and to other organs. When there is no evident lymph node metastasis or distant metastasis, the sentinel node may be examined to confirm absence of axillary lymph node metastasis. The lymph nodes in the axilla drain fluid (lymph) from the breast by interconnecting lymph vessels, and the "sentinel node" is the first node to receive lymph from the particular tumour. If there is no tumour in the sentinel node (and no signs of metastasis to other sites), breast cancer has a very good chance of cure after treatment.
A benign tumor does not spread. If a tumor spreads, it is malignant.
A precarinal lymph node is a lymph node located near the tracheal bifurcation in the chest. It plays a role in filtering and trapping potentially harmful substances, such as cancer cells or bacteria, that may be present in the lymphatic system. Surgical removal or biopsy of precarinal lymph nodes may be necessary in the evaluation and treatment of certain diseases, such as lung cancer.