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Glomus tympanum tumor

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Anonymous

14y ago
Updated: 11/10/2020
Definition

A glomus tympanum tumor is a tumor of the middle ear and bone behind the ear (mastoid).

Alternative Names

Paraganglioma - glomus tympanum

Causes, incidence, and risk factors

A glomus tympanum tumor grows in the temporal bone of the skull, behind the ear drum (tympanic membrane).

This area contains nerve fibers (glomus bodies) that normally respond to changes in body temperature or blood pressure.

These tumors usually occur late in life, around age 60 or 70, but they can appear at any age.

The cause of a glomus tympanum tumor is unknown. Usually, there are no known risk factors. Glomus tumors have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).

Symptoms
  • Hearing problems or loss
  • Ringing in the ear (pulsatile tinnitus)
  • Weakness or loss of movement in the face (facial nerve palsy)
Signs and tests

Glomus tympanum tumors are diagnosed by a physical examination. They may be seen in the ear or behind the ear drum.

Diagnosis also involves scans, including:

Treatment

Glomus tympanum tumors are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms.

Expectations (prognosis)

Patients who have surgery tend to do well. More than 90% of people with glomus tympanum tumors are cured.

Complications

The most common complication is hearing loss.

Nerve damage, which may be caused by the tumor itself or damage during surgery, rarely occurs. Nerve damage can lead to facial paralysis.

Calling your health care provider

Call your health care provider if you notice:

  • Difficulty with hearing or swallowing
  • Problems with the muscles in your face
  • Pulsing sensation in your ear
References

Rucker JC. Cranial neuropathies. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J. Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 74.

Marsh M, Jenkins H. Temporal bone neoplasms and lateral cranial base surgery. In: Cummings CW, Flint PW, Haughey BH, et al. Otolaryngology: Head & Neck Surgery. 4th ed. St. Louis, MO: Mosby;2005;chap 162.

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14y ago

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Glomus jugulare tumor?

DefinitionA glomus jugulare tumor is a tumor of a part of the temporal bone in the skull. This tumor can affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves.Alternative NamesParaganglioma - glomus jugulareCauses, incidence, and risk factorsA glomus jugulare tumor grows in the temporal bone of the skull, in an area called the jugular foramen. The jugular foramen is also where the jugular vein and several important nerves exit the skull.This area contains glomus bodies, which are nerve fibers that normally respond to changes in body temperature or blood pressure.These tumors usually occur later in life, around age 60 or 70, but they can appear at any age. The cause of a glomus jugulare tumor is unknown. Usually, there are no known risk factors. Glomus tumors have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).SymptomsSymptoms may include:Difficulty swallowing (dysphagia)DizzinessHearing problems or lossHearing pulsations in the earHoarsenessPainWeakness or loss of movement in the face (facial nerve palsy)Signs and testsGlomus jugulare tumors are diagnosed by physical examination and various scans, including:Cerebral angiographyCT scanMRI scanTreatmentGlomus jugulare tumors are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms. The main treatment is surgery. Surgery is complex and is usually done by both a neurosurgeon and a head and neck surgeon (neurotologist).In some cases, a procedure called embolization is performed before surgery to prevent the tumor from bleeding too much during surgery.After surgery, radiation therapy may be used to treat any part of the tumor that could not be removed completely.Some glomus tumors can be treated with stereotactic radiosurgery.Expectations (prognosis)Patients who have surgery or radiation tend to do well. More than 90% of those with glomus jugulare tumors are cured.ComplicationsThe most common complications are due to nerve damage, which may be caused by the tumor itself or damage during surgery. Nerve damage can lead to:Change in voiceDifficulty swallowingHearing lossParalysis of the faceCalling your health care providerCall your health care provider if you:Are having difficulty with hearing or swallowingDevelop pulsations in your earNotice a lump in your neckNotice any problems with the muscles in your faceReferencesRucker JC. Cranial neuropathies. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J. Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 74.Marsh M, Jenkins H. Temporal bone neoplasms and lateral cranial base surgery. In: Cummings CW, Flint PW, Haughey BH, et al. Otolaryngology: Head & Neck Surgery. 4th ed. St Louis, Mo: Mosby; 2005:chap 162.Reviewed ByReview Date: 02/01/2010David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Seth Schwartz MD, MPH, Otolaryngologist, Virginia Mason Medical Center, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.


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