A histiocyte is a type of immune cell that eats foreign substances in an effort to protect the body from infection.
Alternative NamesMacrophage
InformationHistiocytes do not travel through the blood. Instead, they remain in one part of the body.
Histiocytes are found in many organs and tissues, including the following:
An abnormal number of histiocytes leads to a disease called histiocytosis X.
ReferencesGoronzy JJ, Weyand Cm. The innate and adaptive immune systems. In: Goldman L, Ausiello D, eds. Cecil Medicine. Philadelphia, Pa: Saunders Elsevier;2007:chap 42.
A histiocyte is a type of immune cell that eats foreign substances in an effort to protect the body from infection.
Alternative NamesMacrophage
InformationHistiocytes do not travel through the blood. Instead, they remain in one part of the body.
Histiocytes are found in many organs and tissues, including the following:
An abnormal number of histiocytes leads to a disease called histiocytosis X.
ReferencesGoronzy JJ, Weyand Cm. The innate and adaptive immune systems. In: Goldman L, Ausiello D, eds. Cecil Medicine. Philadelphia, Pa: Saunders Elsevier;2007:chap 42.
Reviewed ByReview Date: 05/16/2010
David Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The address of the Histiocyte Society is: 332 N Broadway, Pitman, NJ 08071-1022
Histiocyte.
A Macrophage is a white blood cell, produced by Monocytes. Monocytes and Macrophages are both Phagocytes. These work as a part of the human immune system. They act in non-specific "innate" immunity defense and are able to initiate specific "cell-mediated" immunity. The role of a phagocyte is to engulf and "digest"/destroy cell debris or pathogens, such as viruses and bacteria. They are directly responsible for this process called phagocytosis. Macrophages also stimulate Lymphocytes and other immune cells that react to pathogens as what is called an "antigen-presenting" cell, also known as a histiocyte . Macrophages are located throughout the bloodstream, and may be "fixed" or they can be freely motile and capable of amoeboid-like movement.
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