Hypersplenism is a condition in which the spleen is overactive.
Causes, incidence, and risk factorsHypersplenism can be caused by:
Symptoms include:
Ferri FF. Ferri's Clinical Advisor 2007: Instant Diagnosis and Treatment. 9th ed. Philadelphia, Pa: Mosby; 2007:443.
Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:711-12.
Hypersplenism is an overactive spleen. The spleen is an organ found in the upper left side of your belly area. The spleen helps filter old and damaged cells from your bloodstream. If your spleen is overactive, it removes the blood cells too early and too quickly.
The spleen plays an important role in helping your body fight infections. Problems with the spleen can make you more likely to develop infections.
Causes, incidence, and risk factorsHypersplenism can be caused by:
Symptoms include:
Ferri FF. Ferri's Clinical Advisor 2007: Instant Diagnosis and Treatment. 9th ed. Philadelphia, Pa: Mosby; 2007:443.
Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:711-12.
Reviewed ByReview Date: 01/24/2011
Todd Gersten, MD, Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Hypersplenism is not a specific disease but a syndrome (group or cluster of symptoms) that may be associated with different disorders.
Hypersplenism
Secondary hypersplenism results from another disease such as chronic malaria, rheumatoid arthritis, tuberculosis, or polycythemia vera, a blood disorder.
Symptoms of hypersplenism include easy bruising, easy contracting of bacterial diseases, fever, weakness, heart palpitations, and ulcerations of the mouth, legs and feet.
hypersplenism
Prognosis depends on the underlying cause and progression of the disease. Left untreated, spleen enlargement can lead to serious complications. Hypersplenism can also lead to complications due to decreased blood cell counts.
Splenectomies are performed for a variety of different reasons and with different degrees of urgency. Most splenectomies are done after a patient has been diagnosed with hypersplenism.
There are certain factors that can cause low polymorphs in the blood. Some of these are infection, certain medications, deficiencies, hypersplenism or radiation therapy.
Spleen is the major organ of lymphatic system of the body. But you have to remove the enlarged spleen to prevent, what is called as hypersplenism.
Infection could cause a low polymorphs or white blood cell count. Other causes may include vitamin deficiencies, certain medications, hypersplenism or radiation therapy.
The medical term for a decrease in the neutrophil count is neutropenia. Some of the causes for decreased neutrophil or white blood cell count include congenital disorders, infections, hypersplenism and vitamin deficiencies.
Infection could cause a low polymorphs or white blood cell count. Other causes may include vitamin deficiencies, certain medications, hypersplenism or radiation therapy.