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Hypersplenism

Updated: 9/27/2023
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13y ago

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Definition

Hypersplenism is a condition in which the spleen is overactive.

Causes, incidence, and risk factors

Hypersplenism can be caused by:

Symptoms

Symptoms include:

  • Enlarged spleen
  • Low level of one or more types of blood cells
  • Premature feeling of fullness after eating
  • Stomach pain on the left side
References

Ferri FF. Ferri's Clinical Advisor 2007: Instant Diagnosis and Treatment. 9th ed. Philadelphia, Pa: Mosby; 2007:443.

Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:711-12.

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13y ago
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Wiki User

12y ago
Definition

Hypersplenism is an overactive spleen. The spleen is an organ found in the upper left side of your belly area. The spleen helps filter old and damaged cells from your bloodstream. If your spleen is overactive, it removes the blood cells too early and too quickly.

The spleen plays an important role in helping your body fight infections. Problems with the spleen can make you more likely to develop infections.

Causes, incidence, and risk factors

Hypersplenism can be caused by:

Symptoms

Symptoms include:

  • Enlarged spleen
  • Low level of one or more types of blood cells
  • Premature feeling of fullness after eating
  • Stomach pain on the left side
References

Ferri FF. Ferri's Clinical Advisor 2007: Instant Diagnosis and Treatment. 9th ed. Philadelphia, Pa: Mosby; 2007:443.

Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:711-12.

Reviewed By

Review Date: 01/24/2011

Todd Gersten, MD, Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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Related questions

What is hypersplenism?

Hypersplenism is not a specific disease but a syndrome (group or cluster of symptoms) that may be associated with different disorders.


What is the increased function of the spleen?

Hypersplenism


What causes secondary hypersplenism?

Secondary hypersplenism results from another disease such as chronic malaria, rheumatoid arthritis, tuberculosis, or polycythemia vera, a blood disorder.


What are some symptoms of hypersplenism?

Symptoms of hypersplenism include easy bruising, easy contracting of bacterial diseases, fever, weakness, heart palpitations, and ulcerations of the mouth, legs and feet.


When spleen removes blood components at an excessive rate what is it?

hypersplenism


What is the prognosis of hypersplenism?

Prognosis depends on the underlying cause and progression of the disease. Left untreated, spleen enlargement can lead to serious complications. Hypersplenism can also lead to complications due to decreased blood cell counts.


Why are splenectomies done?

Splenectomies are performed for a variety of different reasons and with different degrees of urgency. Most splenectomies are done after a patient has been diagnosed with hypersplenism.


What causes low Polymorph's in the blood?

There are certain factors that can cause low polymorphs in the blood. Some of these are infection, certain medications, deficiencies, hypersplenism or radiation therapy.


Which is the major organ of lymphatic system?

Spleen is the major organ of lymphatic system of the body. But you have to remove the enlarged spleen to prevent, what is called as hypersplenism.


What cause a low polymorphs?

Infection could cause a low polymorphs or white blood cell count. Other causes may include vitamin deficiencies, certain medications, hypersplenism or radiation therapy.


What is the decrease in the number of neutrophils?

The medical term for a decrease in the neutrophil count is neutropenia. Some of the causes for decreased neutrophil or white blood cell count include congenital disorders, infections, hypersplenism and vitamin deficiencies.


What cause a low polymorphs count?

Infection could cause a low polymorphs or white blood cell count. Other causes may include vitamin deficiencies, certain medications, hypersplenism or radiation therapy.