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Hypogonadotropic hypogonadism is absent or decreased function of the male testes or the female ovaries. It is considered a form of secondary hypogonadism, which means the condition is due to a problem with the pituitary or hypothalamus gland.
See also: Hypogonadism
Alternative NamesGonadotropin deficiency; Secondary hypogonadism; Kallmann syndrome
Causes, incidence, and risk factorsHypogonadotropic hypogonadism is caused by a lack of the gonadal stimulating pituitary hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH).
Normally, the hypothalamus in the brain releases gonadotropin-releasing hormone (GnRH), which stimulates the pituitary gland to release other hormones, including FSH and LH. These hormones tell the female ovaries and male testes to secrete hormones that are responsible for normal sexual development in puberty. A disruption in this chain of events causes a deficiency of the sex hormones and prevents normal sexual maturity.
Failure of the hypothalamus is most commonly a result of Kallmann syndrome. Kallmann syndrome is an inherited form of hypogonadotropic hypogonadism that can be associated with a loss of smell.
Symptoms- Absence of secondary sexual characteristics such as pubic, facial, and underarm hair
- Inability to smell (in some cases)
- Lack of development at puberty (may involve incomplete development or a significant delay in development)
- Underdeveloped testicles
- Short stature(in some cases)
Tests that may be done include:
- Blood tests to measure various hormone levels
- LH response to GnRH
- MRI of the head
Treatment depends on the source of the problem but may involve:
- Injections of testosterone
- Slow-release testosterone skin patch
- Estrogen and progesterone pills
- GnRH injections
- Testosterone gels
With the right hormone treatment, the person can begin puberty and fertility may be restored.
Complications- Delayed puberty
- Infertility
- Low self-esteem due to late start of puberty (emotional support may be helpful)
Call your health care provider if your child does not enter puberty as expected.
PreventionPrevention depends on the cause. People who have a family history of inherited conditions associated with hypogonadism may benefit from genetic counseling. Preventing serious head injuries reduces the risk of pituitary injury-associated hypogonadotropic hypogonadism.
ReferencesAACE Thyroid Task Force. AACE Hypogonadism Guidelines. Endocr Pract. 2002;8(6):441.
Styne DM, Grumbach. Puberty: Ontogeny, neuroendocrinology, physiology, and disorders. In: Kronenberg HM, Shlomo M, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier;2008:chap 24.
What else can I help you with?
What is the prefix for hypogonadism?
The prefix for hypogonadism is "hypo", which means decreased. In this manner, hypogonadism refers to the reduction of the physiological activity of the gonads.
Can hypogonadism be cured?
Hypogonadism cannot be "cured" but can be successfully treated in both men and women with hormone replacement therapy (HRT).
What to treat hypogonadism?
Hypogonadism is treated with hormone replacement therapy. This is usually in the form of testosterone. It can be an injection, or a patch or in a gel formation.
Is clostil effective for men infertility?
Clomiphene citrate, often referred to as Clostil, can be effective in treating male infertility, particularly in cases of hypogonadotropic hypogonadism or low testosterone levels. It works by stimulating the hypothalamus and pituitary gland to increase the production of hormones that promote sperm production. However, its effectiveness varies among individuals, and it is essential for men to consult a healthcare professional for a proper diagnosis and personalized treatment plan.
What is the icd 9 code hypogonadism?
The ICD-9 code for hypogonadism is 256.3. This code generally refers to disorders of the testes or ovaries leading to reduced hormone production. It is important to note that ICD-9 has been largely replaced by ICD-10, which provides more specific codes for various types of hypogonadism.
When 18 year old male diagnose with central hypogonadism will penis still grow?
If you have central hypogonadism, you need to contact your endocrinologist. They will be able to direct any hormone treatments that may be available for you.
What term describes the decrease of the male hormone testosterone in the aging male?
Hypogonadism, specifically late-onset hypogonadism, is the term that describes the decrease of testosterone in aging males. It can lead to symptoms like reduced libido, fatigue, and decreased muscle mass.
Can hypogonadism cause weight gain?
Yes! and I'll tell you why. If you have true hypogonadism with blood levels under 200 ng/dl your body may have high estradiol. Witch makes you a woman inside. You will get higher fat in your body. ie: hips belly breast
What are the risks hypogonadism?
Threat issues for hypogonadism consist of : 1. Kallmann syndrome disorder 2. Undescended testicles as an infant 3. Mumps bacterial infection which affects your testicles 4. An injury to your testicles 5. Testicular or even pituitary tumors 6. HIV/AIDS 7. Klinefelter syndrome disorder 8. Hemochromatosis 9. Past chemotherapy or maybe radiation treatment Hypogonadism might be hereditary . In case these kinds of threat issues are in your family medical background ,
Which medications are used to correct hormone deficiency in hypogonadism and treat delayed puberty in males?
Human Growth Hormone. HGH
What some diseases of the gonads?
There are actually several diseases of the gonads in human males. Some of these are testicular cancers, testicular torsion, hypogonadism, and epididymitis.
What is the cause of Kallmann syndrome?
Kallmann syndrome is an example of hypogonadism (decreased functioning of the sex hormone-producing glands) caused by a deficiency of gonadotropin-releasing hormone
