Metabolic acidosis is a condition in which there is too much acid in the body fluids.
Alternative NamesAcidosis - metabolic
Causes, incidence, and risk factorsMetabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body. There are several types of metablic acidosis:
Other causes of metabolic acidosis include:
Most symptoms are caused by the underlying disease or condition that is causing the metabolic acidosis. Metabolic acidosis itself usually causes rapid breathing. Confusion or lethargy may also occur. Severe metabolic acidosis can lead to shock or death. In some situations, metabolic acidosis can be a mild, chronic (ongoing) condition.
Signs and testsArterial blood gas analysis or a serum electrolytes test (such as a basic metabolic panel) will confirm acidosis is present and determine whether it is respiratory acidosis or metabolic acidosis.
Other test may be needed to determine the cause of the acidosis.
TreatmentTreatment is aimed at the underlying condition. In certain circumstances, sodium bicarbonate (baking soda) may be given to improve the acidity of the blood.
Expectations (prognosis)What can be expected will depend on the underlying disease causing the metabolic acidosis.
ComplicationsWhen very severe, metabolic acidosis can lead to shock or death.
Calling your health care providerSeek medical treatment if you develop symptoms of any disease that can cause metabolic acidosis.
PreventionKeeping type 1 diabetes under control may help prevent diabetic ketoacidosis, one type of metabolic acidosis.
ReferencesSeifter JL. Acid-base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 119.
Metabolic acidosis is a condition in which there is too much acid in the body fluids.
Alternative NamesAcidosis - metabolic
Causes, incidence, and risk factorsMetabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body.
There are several types of metabolic acidosis:
Other causes of metabolic acidosis include:
Most symptoms are caused by the underlying disease or condition that is causing the metabolic acidosis. Metabolic acidosis itself usually causes rapid breathing. Confusion or lethargy may also occur. Severe metabolic acidosis can lead to shock or death. In some situations, metabolic acidosis can be a mild, chronic (ongoing) condition.
Signs and testsArterial blood gas analysis or a serum electrolytes test (such as a basic metabolic panel) will confirm acidosis is present and determine whether it is respiratory acidosis or metabolic acidosis.
Other test may be needed to determine the cause of the acidosis.
TreatmentTreatment is aimed at the underlying condition. In certain circumstances, sodium bicarbonate (baking soda) may be given to improve the acidity of the blood.
Expectations (prognosis)What can be expected will depend on the underlying disease causing the metabolic acidosis.
ComplicationsWhen very severe, metabolic acidosis can lead to shock or death.
Calling your health care providerSeek medical treatment if you develop symptoms of any disease that can cause metabolic acidosis.
PreventionKeeping type 1 diabetes under control may help prevent diabetic ketoacidosis, one type of metabolic acidosis.
ReferencesSeifter JL. Acid-base disorders.In: Goldman L, Schafer AI, eds.Cecil Medicine. 24th ed.Philadelphia,PA: Saunders Elsevier; 2011:chap 120.
Reviewed ByReview Date: 11/17/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Metabolic acidosis
DefinitionAcidosis is a condition in which there is excessive acid in the body fluids. It is the opposite of alkalosis (a condition in which there is excessive base in the body fluids).Causes, incidence, and risk factorsThe kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory acidosis or metabolic acidosis.Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused by a decreased ability to remove carbon dioxide from the body through effective breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include:Chest deformities, such as kyphosisChest injuriesChest muscle weaknessChronic lung diseaseOveruse of sedative drugsMetabolic acidosis develops when too much acid is produced or when the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis:Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes.Hyperchloremic acidosis results from excessive loss of sodium bicarbonate from the body, as can happen with severe diarrhea.Lactic acidosisis a buildup of lactic acid. This can be caused by: AlcoholCancerExercising vigorously for a very long timeLiver failureLow blood sugar (hypoglycemia)Medications such as salicylatesProlonged lack of oxygen from shock, heart failure, or severe anemiaSeizuresOther causes of metabolic acidosis include:Kidney disease(distal renal tubular acidosis and proximal renal tubular acidosis)Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanolSevere dehydrationSymptomsSee: Metabolic acidosis or Respiratory acidosisSigns and testsArterial or venous blood gas analysisSerum electrolytesUrine pHAn arterial blood gas analysis or serum electrolytes test, such as a basic metabolic panel, will confirm that acidosis is present and indicate whether it is metabolic acidosis or respiratory acidosis. Other tests may be needed to determine the cause of the acidosis.TreatmentTreatment depends on the cause. See the specific types of acidosis.Expectations (prognosis)Acidosis can be dangerous if untreated. Many cases respond well to treatment.ComplicationsSee the specific types of acidosis.Calling your health care providerAlthough there are several types of acidosis, all will cause symptoms that require treatment by your health care provider.PreventionPrevention depends on the cause of the acidosis. Normally, people with healthy kidneys and lungs do not experience significant acidosis.ReferencesSeifter JL. Acid-base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 119.
acidosis
True/Yes Acidosis is defined as a blood pH less than normal
The ratio of inorganic phosphate to phosphocreatine reflects the relative metabolic rate of mitochondrial respiration (V) and the extrapolated maximum capacity of oxidative metabolism (Vm). Normal humans vary considerably in their metabolic response to exercise. These differences are reflected in their Vms and the degree of acidosis during exercise. Active muscles in endurance trained athletes have higher Vms and faster recovery rates than normal controls. Preliminary studies have been done to assess muscle glycolytic capacity by measuring the degree of acidosis during ischaemic exercise. Exercise-induced muscle injury can be detected as an increased inorganic phosphate to phosphocreatine ratio in resting muscle.
respiratory alkalosis would cause metabolic acidosis
Metabolic acidosis
The medical application of acidosis is to rectify the the pH of the blood. There are two main type of acidosis which are respiratory and metabolic acidosis.
The PO2 does decrease in metabolic acidosis, Similarly, there is a decrease in the pH and HCO3 levels. Metabolic acidosis is a condition where the body is producing too much acid.
yes
Metabolic acidosis
Metabolic acidosis
metabolic acidosis
Acidosis is high levels of acidity in the blood and other body tissue, occuring when the arterial pH falls below 7.35. The two types of acidosis are metabolic acidosis and respiratory acidosis.
Acidosis following thermal injury is common, and is most pronounced on admission. The acidosis is usually compensated by respiratory alkalosis. Acidosis develops within hours after > 30% burns. Has both metabolic and respiratory components. Former due to products of heat-damaged tissues and relative hypoxia.
Metabolic acidosis occurs when the body does not get rid of the build up of acids in the body. Acidosis can occur due to kidney failure, uncontrolled diabetes, alcohol poisoning, and prolonged lack of oxygen.
A metabolic acidosis will have a low HCO3(less than 22) and a low base access( less than-2) there may be a compensatory low CO2 (less than 4,7kPa. But in respiratory acidosis the CO2 is high( more than 6.0k,Pa) and the O2 may be low