A parathyroid biopsy is a procedure to remove a small piece of a parathyroid gland. The parathyroid glands are the four glands behind the thyroid in the neck.
Alternative NamesBiopsy - parathyroid
How the test is performedA parathyroid biopsy is done while the patient is awake. Using an ultrasound machine, the health care provider locates the gland of concern. A thin needle is inserted directly into the gland, and a small piece of tissue is removed.
The tissue is sent to a laboratory, where it is examined under a microscope. The tissue's levels of parathyroid hormone (PTH) will also be checked. PTH is secreted by the parathyroid glands and helps control the body's calcium levels.
How to prepare for the testTell your health care provider if you have any drug Allergies or bleeding problems, or if you are pregnant. You must sign a consent form. Also, make sure the health care provider knows about all the medications you are taking.
How the test will feelThe test feels like a quick shot (injection). You may feel a sting as the needle is inserted into the gland.
Why the test is performedThis procedure is most often done to confirm the cause of hyperparathyroidism.
It may also be done if an ultrasound exam shows a larger than normal parathyroid gland. Your doctor can only see a parathyroid gland on ultrasound if it is abnormally swollen.
Normal ValuesThere is no swelling, hormone levels appear normal, and cells from the tissue sample are normal.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results meanThe test confirms that a parathyroid gland is enlarged, if hormone levels are too high, or if cells from the sample are abnormal.
Abnormal results may be due to:
You can return to normal activities the same day.
A parathyroid biopsy is the removal of a small piece of a parathyroid gland for examination under a microscope. The parathyroid glands are found just behind the thyroid gland on each side of the neck.
See also:
Alternative NamesBiopsy - parathyroid
How the test is performedThere are two parathyroid glands on either side of the neck, making a total of four glands. The parathyroid glands cannot be felt with the hands.
A parathyroid biopsy is done while you are awake. Using an ultrasound machine, the health care provider locates the gland that is of concern. A thin needle is inserted directly into the gland, and a small piece of tissue is removed. The procedure takes 10 - 30 minutes.
The tissue is sent to a laboratory, where it is examined under a microscope. The levels of parathyroid hormone (PTH) in your blood will also be checked.
How to prepare for the testTell your health care provider if you have any drug allergies or bleeding problems, or if you are pregnant.
Make sure the health care provider knows about all the medications you are taking. Tell your health care provider if you are taking any blood thinning medications (aspirin, heparin, Lovenox), because you may have to stop taking them a few days before the procedure.
You must sign a consent form.
How the test will feelThe test feels like a quick needle jab or stick. You may feel a sting as the needle is inserted into the gland. Most people do not need any pain medication.
Why the test is performedThe parathyroid glands release parathyroid hormone (PTH). This hormone controls the level of calcium in the body.
This procedure is most often done to rule out cancer as a cause of high parathyroid hormone levels.
It may also be done if an ultrasound exam shows a larger-than-normal parathyroid gland.
Normal ValuesThere is no swelling, hormone levels appear normal, and cells from the tissue sample are normal.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results meanThe test confirms that a parathyroid gland is enlarged, if hormone levels are too high, or if cells from the sample are abnormal. Abnormal PTH levels may also be due to hypercalcemia.
Abnormal results may be due to:
The main risks of the procedure are bruising and bleeding into or around the thyroid gland. If bleeding is severe, it may put pressure over the windpipe (trachea). This complication is rare.
In rare cases, some people may develop temporary hoarseness when the nerve that runs close to the parathyroid glands is injured.
Special considerationsYou can return to normal activities the same day.
Reviewed ByReview Date: 09/10/2010
Shabir Bhimji, MD, PhD, Specializing in Cardiothoracic and Vascular Surgery, Midland, TX. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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